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Hyalovet (Hyaluronate Sodium) Injection 20 mg/2 ml (10 mg/ml) Rx

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Product Description
Hyalovet (Hyaluronate Sodium) Injection 20 mg/2 ml (10 mg/ml) is indicated for the intra-articular treatment of carpal or fetlock joint dysfunction in horses due to acute or chronic, non-infectious synovitis associated with equine osteoarthritis. Available in a prefilled 2 ml syringe or 2 ml vial.
What is Hyalovet (Hyaluronate Sodium) Injection 20 mg/2 ml (10 mg/ml)?
Hyalovet (Hyaluronate Sodium) Injection is for the intra-articular treatment of carpal or fetlock joint dysfunction in horses due to acute or chronic, non-infectious synovitis associated with equine osteoarthritis.
Who is Hyalovet (Hyaluronate Sodium) Injection 20 mg/2 ml (10 mg/ml) for?
Horses
Why use Hyalovet (Hyaluronate Sodium) Injection 20 mg/2 ml (10 mg/ml)?
-Treats carpal or fetlock joint dysfunction in horses due to acute or chronic, non-infectious synovitis associated with equine osteoarthritis -Molecular filtration technology removes extraneous fractions and impurities -FDA approved hyaluronic acid -No refrigeration required, stores at room temperature
How does Hyalovet (Hyaluronate Sodium) Injection 20 mg/2 ml (10 mg/ml) work?
Hyaluronic acid is the prototype of a wide range of saccharide biopolymers (glycosaminoglycans or mucopolysaccharides) consisting of repeating disaccharide units of N-acetyl-D-glucosamine and D-glucuronic acid linked by beta 1-3 and beta 1-4 glycosidic bonds. A component of all mammalian connective tissue, hyaluronic acid confers viscoelastic and lubricating properties to synovial fluid1 and structural integrity to cartilage matrix2. As a therapeutic agent, hyaluronic acid injected into arthritic joints has been shown, in a variety of animal model systems including horses3, to improve joint function and to activate tissue repair processes in articular cartilage. Hyalovet (hyaluronate sodium) is clear, colorless, viscous solution of a specific fraction of highly purified hyaluronic acid obtained by a molecular filtration procedure from biological material (rooster combs). The specific hyaluronic acid fraction from which Hyalovet is made has a high degree of molecular definition with an average molecular weight of 500,000-730,000 D.
Manufacturer:
Boehringer Ingelheim
Active Ingredients(s):
Hyaluronate Sodium 20 mg/2 ml (10 mg/ml)
How is Hyalovet (Hyaluronate Sodium) Injection 20 mg/2 ml (10 mg/ml) sold?
2 ml prefilled syringe or 2 ml vial
What are the side effects of Hyalovet (Hyaluronate Sodium) Injection 20 mg/2 ml (10 mg/ml)?
No known side effects. As with any intra-articular injection a mild inflammatory response (tenderness, heat and swelling) may be seen in the joint following Hyalovet injection. The response is self limiting but may last from two to five days after treatment. If inflammation is excessive or severe contact your Veterinarian.
What special precautions are there?
Keep away from children. Do not use in horses intended for human consumption. Not for human use. Hyalovet Injection must not be administered intravascularly. Used or partially used syringes should be crushed and disposed of in an approved landfill.
What to do if overdose?
Contact your nearest emergency animal hospital
How can I store Hyalovet (Hyaluronate Sodium) Injection 20 mg/2 ml (10 mg/ml)?
Store at or below 25°C (77°F)
Overview
Use as directed by your Veterinarian

Dosage and Administration :

The recommended dose of Hyalovet (hyaluronate sodium) is 2 mL (20 mg hyaluronate sodium) in small or medium sized joints (carpus, fetlock) given by intra-articular injection. More than one joint may be treated at the same time. If necessary, the injection may be repeated after one or more weeks, but not to exceed 2 injections per week for a total of 4 weeks.

Hyalovet should be injected using strict aseptic technique. Excess synovial fluid should be removed prior to injection.

For best results horses should be given two days of rest or limited exercise before resuming normal training.
Main Ingredients
Hyaluronate Sodium 20 mg/2 ml (10 mg/ml)

Each filled 2 mL glass syringe or 2 mL glass vial contains :
Hyaluronate sodium 20.0 mg
Sodium chloride 17.0 mg
Monobasic sodium phosphate 0.1 mg
Dibasic sodium phosphate 1.2 mg
Water for injection q.s., 2 mL